Effect of Taurine-Zinc Coordination Compound on NADPH-d Positive Neurons in Cerebral Cortex of Mercury-Exposed Rats
- VernacularTitle:牛磺酸锌对染汞大鼠大脑皮层NADPH-d阳性神经元的影响
- Author:
Jianzhong ZHU
;
Wentao ZHAO
;
Jisheng LI
- Publication Type:Journal Article
- Keywords:
Mercury;
Neuron;
Taurine-zinc coordination compound;
Cerebral cortex;
Nitric oxide synthase
- From:
Journal of Environment and Health
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the antagonism of taurine-zinc coordination compound (TZC) to the adverse effect of mercury (Hg) on the neurons in the cerebral cortex. Methods 32 male Wistar rats aged 21days were randomly divided into 4 groups, one control group (fed on distilled water), three experimental groups fed on HgCl2 (0.06 g/L), HgCl2+0.23 g/L TZC and HgCl2+0.46 g/L TZC respectively, treated for one month. The NOS activity in the cerebral cortex neurons was determined by NADPH-d histochemistry. Results NADPH-d positive neurons increased in HgCl2 group (P
