Relationship between bedtime blood glucose level and nocturnal hypoglycemia observed with continuous glucose monitoring system in type 2 diabetic patients
- VernacularTitle:动态血糖监测探讨2型糖尿病患者睡前血糖和夜间低血糖的关系
- Author:
Guofu WU
;
Yifeng MAI
;
Wei WO
;
Chunyan YU
;
Yinhuan WU
;
Jiangping JIAO
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus, type 2;
Continuous glucose monitoring system;
Hypoglycemia, nocturnal
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Blood glucose levels of 220 days were recorded in 85 type 2 diabetic patients for monitoring glycemia for 48-72 h each one by the continuous glucose monitoring system (CGMS). Frequencies of nocturnal hypoglycemia (blood glucose≤2. 8mmol/L) were estimated when bedtime blood glucose levels were≤4.4mmol/ L,≤5.0mmol/L,≤5. 6mmol/L,≤6.1mmol/L,≤6. 7mmol/L, or≤7. 2mmol/L respectively. Nocturnal hypoglycemia occurred in 39 nights of 220 days (17.7%) of 26 patients and their bedtime blood glucose level was (4.4?2.6)mmol/L with a range from 2. 2 to 12. 6 mmol/L. Using a cut-off of bedtime blood glucose at≤6. 7 mmol/L, area under the ROC curve was reached maximal value (0. 359?0. 046). The positive predictive value was 25% and the negative predictive value was 91. 7%. CCMS is a useful tool to detect unaware nocturnal hypoglycemia.
