Tumor necrosis factor-? gene polymorphism in obese patients with type 2 diabetes mellitus
- VernacularTitle:肥胖的2型糖尿病患者肿瘤坏死因子?基因多态性的研究
- Author:
Pingxia XIANG
;
Yan LI
;
Pingan ZHANG
;
Zhongyuan WEN
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Tumor necrosis factor-?;
Obesity;
Polymorphism (Genetics)
- From:
Chinese Journal of Endocrinology and Metabolism
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
CT and TT genotype frequencies of TNF-? gene at -857 site in obese patients with type 2 diabetes mellitus (DM)andcontrolgroupswithoutobesity were 0.396, 0.020 and 0.179, 0.000, and T allele 0.220 and 0.090, respectively. This finding suggests that mutation is associated with type 2 DM in obese subjects.
