Effect and clinical significance of Tacrolimus on serum interleukin-2(IL-2),soluble interleukin-2 receptor(sIL-2R) expression in refractory nephrotic syndrome
- VernacularTitle:普乐可复对难治性肾病综合征患者血清IL-2、sIL-2R的影响及其临床意义
- Author:
Lining MIAO
;
Yanan ZHANG
;
Shengmao LIU
;
Yingchun CUI
- Publication Type:Journal Article
- Keywords:
Tacroliumus;
Refractory nephritic syndrome;
IL-2;
sIL-2R
- From:
Chinese Journal of Immunology
1985;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of Tacroliums(FK506) on the significance of IL-2 and sIL-2R expression in refractory nephrotic syndrome. Methods: The expression of IL-2 and sIL-2R were evaluated by enzyme-linked immunosorbent assay (ELISA) on both pretreatment and post-treatment groups, and supervise the changes of 24hours urinary protein,serum albumin and lipid. Results:Serum IL-2 and sIL-2R level were higher in pre-treatment group than in normal control group(P
