The phenotype of the immortalized human odontoblast-like cell line
- VernacularTitle:永生化人成牙本质细胞样细胞系的转化特征
- Author:
Hanguo WANG
;
Mingzhen XIAO
;
Shouliang ZHAO
- Publication Type:Journal Article
- Keywords:
Transformation;
Cell line;
Odontoblast;
Human
- From:
Journal of Practical Stomatology
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To determine whether the immortalized human odo nt oblast-like cell line hTERT-hOd-l has transformed phenotype. Methods: The tumorigenicity, anchorage-independent growth, serum dependence and contact inhibition of the immortalized human odontoblast-like cell line hTERT- hOd-l were observed during continuous culture in vitro. Results: The cells showed to be nontumorigenic in nude mice, and to have no anchorag e-independent growth. The cells maintained the normal serum dependence and cont act inhibition. Conclusion:hTERT-hOd-l is a normal cell line w ithout obvious transformed phenotype.
