The Clinical Application of Hepacellular MRI Contrast Agent Mn-DPDP
- VernacularTitle:组织特异性对比剂——Mn-DPDP的临床应用
- Author:
Aili CHEN
;
Yong WANG
;
Jinzhong JI
;
Sifu YANG
- Publication Type:Journal Article
- Keywords:
liver;
pancreas;
MRI;
Mn-DPDP;
clinical application
- From:
Journal of Practical Radiology
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the enhancement characteristics of the mass of liver and pancreas on Mn-DPDP enhanced MRI. Methods Mn-DPDP enhanced MRI were carried out in 25 cases, of which 15 cases had examined by Gd-DTPA-enhanced MRI. Conventional plain with SE T 1WI、FSE T 2WI were done in all patient. SE T 1WI and FSPGR T 1WI were performed during 40 minutes～4 hours after the administration of Mn-DPDP, with a dose of 0.5 ml/kg.Parts of the patients were repeat examined 24 hours after the administration of Mn-DPDP. Results Among 10 cases of hepatocelluler carcinoma, slightly heterogeneous enhancement were found in 8 cases.hemi-ring enhancement were found in 2 cases. 2 cases of liver cirrhosis had apparently nodular homogenous enhancement and their signal intensity were higher than normal liver tissue. No enhancement were found in 2 cases of hemangioma, 2 cases of liver metastases and 1 case of hepatic cyst. Also no enhancement were found in 8 cases of pancreatic carcinoma, but the tissue of pancreas around the tumor were enhanced remarkably. Conclusion The Mn- DPDP can show remarkably enhancement of normal liver and pancreas.The medicine's peak value keeps on time grows, can provide plentiful scanning time windows.
