Study of angiogensis of ovarian serous neoplasms and ras p21 expression as well as their clinical prognosis
- VernacularTitle:卵巢浆液性肿瘤血管生成与rasp21表达及临床预后
- Author:
Yumei LIAO
;
Lihui WEI
;
Zhenghui GENG
- Publication Type:Journal Article
- Keywords:
Ovarian neoplasms Angiogensis ras gene Immunohistochemistry Prognost
- From:
Clinical Medicine of China
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between tumor angiogenesis and expression of ras p21 protein as well as the prognosis in serous ovarian neoplasms.Methods Microvessel density (MCD) and expression of ras p21 protein in issues of 10 adenomas and 50 serous ovarian cancers were observed by immunohistochemical staining methods with monoclonal antibody CD 34 to mark vascular endotheliocytes.Results Microvessel density in specimens from over expression of ras p21 protein and from grade Ⅱ and Ⅲ was significantly higher than that in specimens from low expression or negative expression of ras p21 protein as well as from grade I (P
