Association between the insertion/deletion polymorphism of angiotensin converting enzyme gene and the myocardial infarction
- VernacularTitle:血管紧张素转化酶基因的插入/缺失多态性与心肌梗死的关系
- Author:
Lihong TIAN
;
Haosheng HUI
;
Caiqiong LIU
- Publication Type:Journal Article
- Keywords:
Angiotensin converting enzyme Gene polymorphism Myocardial infarctioL
- From:
Clinical Medicine of China
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association between the insertion/deletion(I/D) polymorphism of angiotensin converting enzyme (ACE) gene and the myocardial infarction (MI) among Chinese population. Methods Polymerase chain reaction(PCR) was applied to the examination of ACE gene polymorphism. A comparison was performed between 50 patients with MI and another 50 healthy subjects.Results The frequencies of DD genotype (0.38) and D allele (0.58) were both higher among the MI group than that among the control group (0.16 and 0.41 respectively,P
