Drug Interactions of Proton Pump Inhibitors with Clopidogrel in Patients Underwent PCI
- VernacularTitle:PCI术后患者联合使用质子泵抑制剂对氯吡格雷疗效的影响
- Author:
Xu TANG
;
Qili BI
;
Liumei FAN
- Publication Type:Journal Article
- Keywords:
Clopidogrel;
Proton pump inhibitor;
Aspirin;
Drug interactions;
Retrospective analysis
- From:
China Pharmacy
2007;0(32):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). But the incidence of rehospitalization in combination group because of adverse cardiovascular events wasn’t more two times than that of non-combination group (OR=2.07; 95% confidence interval ranged from 1.87 to 2.20). CONCLUSION: The results of study are similar to other studies of foreign countries. PPI can influent the anti-platelet effect of clopidogrel so as to increase the incidence of rehospitalization risk resulted from adverse cardiovascular events. Physicians should apply PPI with cautions.
