Polymorphisms of monoamine oxidase gene and its correlation with certain psychiatric disorders
- VernacularTitle:MAO基因遗传多态性及与精神疾病相关性研究进展
- Author:
Lu ZHANG
;
Baojie WANG
;
Mei DING
;
Hao PANG
;
Jinjing ZHANG
- Publication Type:Journal Article
- Keywords:
forensic psychiatry;
monoamine oxidase(MAO);
polymorphisms;
psychiatric disorder;
individual identification
- From:
Chinese Journal of Forensic Medicine
1988;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Monoamine oxidase(MAO) is a kind of mitochondrial outer membrane enzyme that degrades biogenic amines,such as catecholamine and serotonin.It has a variety of biological functions,and can be found in various human tissues,including nervous system.Two MAO enzymes,MAO-A and MAO-B have been identified.MAO gene has polymorphisms,and some of which have a close relationship with certain psychic diseases,such as major depression,alcoholism,antisocial personality disorder and so on.MAO gene can acts as a new forensic individual identification and parentage testing genetic marker or legal psychiatry testing referential genetic marker.
