Multiple brown tumors of the jaws in primary hyperparathyroidism.
- Author:
Kyoung A KIM
1
;
Kwang Joon KOH
Author Information
1. Department of Oral and Maxillofacial Radiology, School of Dentistry, and Institute of Oral Bio Science, Chonbuk National University, Korea. beam@jbnu.ac.kr
- Publication Type:Case Report
- Keywords:
Osteitis Fibrosa Cystica;
Hyperparathyroidism;
Mandible;
Maxilla
- MeSH:
Alkaline Phosphatase;
Aneurysm;
Bone Cysts;
Diagnosis, Differential;
Follow-Up Studies;
Granuloma, Giant Cell;
Humans;
Hypercalcemia;
Hyperparathyroidism;
Hyperparathyroidism, Primary;
Hypophosphatemia;
Jaw;
Mandible;
Maxilla;
Multiple Myeloma;
Osteitis Fibrosa Cystica;
Parathyroid Neoplasms;
Recurrence;
Thyroid Gland
- From:Korean Journal of Oral and Maxillofacial Radiology
2010;40(3):149-153
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Brown tumor is usually diagnosed at the terminal stage of hyperparathyroidism. Diagnosis of this tumor is confirmed by endocrinologic investigations along with clinical and radiographic examination. Radiographical differential diagnosis of this tumor includes central giant cell granuloma, aneurysmal bone cyst, metastatic tumor, multiple myeloma, and Paget disease. This report presents a rare case of multiple brown tumors occurring at the maxilla and mandible, which was initially misdiagnosed as central giant cell granuloma. Plain radiographs demonstrated multiple well-defined multilocular radiolucency. CT images showed soft tissue mass with low attenuated lesions, perforation of the lingual cortical plate, and a heterogeneous mass at the right thyroid lobe. These findings were consistent with parathyroid adenoma. The patient had hypercalcemia, hypophosphatemia, and elevated alkaline phosphatase level. Surgical excision of the tumor was performed. No recurrence was observed during a 28-month follow-up.
