Compatible Stability of Cefotiam Hydrochloride for Injection with Fructose Injection
- VernacularTitle:注射用盐酸头孢替安与果糖注射液的配伍稳定性考察
- Author:
Lei ZHOU
;
Peihong MIAO
;
Zhongjie HU
- Publication Type:Journal Article
- Keywords:
UV spectrophotometry;
Cefotiam hydrochloride;
Fructose;
Stability
- From:
China Pharmacy
2007;0(29):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To investigate the compatible stability of cefotiam hydroloride for injection with fructose injection.METHODS: The content changes of the mixture within 8h at 25℃ were determined by UV spectrophotometry,and its external appearance was observed,and the pH value as well as particle size of the mixture were measured.RESULTS: The mixture was clear within 6h,showing no visible changes in appearance,pH value and contents of cefotiam,with particles in line with the standard stated in China Pharmacopeia(2005 edition).CONCLUSION: The mixture of ceforiam hydrochloride for injection and fructose injection is stable within 6h.
