Proliferating T cells and dendritic cells in the skin lesions of patients with mycosis fungoides
- VernacularTitle:蕈样肉芽肿皮损中增生性T细胞与树突细胞的研究
- Author:
Aiping FENG
;
Jing ZHAO
;
Yan WU
;
Yue QIAN
;
Siyuan CHEN
;
Xin LIAN
;
Yating TU
- Publication Type:Journal Article
- Keywords:
Lymphoma, T-cell, cutaneous;
Dendritic cells;
K.i-67 antigen;
T-lymphocytes;
CLA
- From:
Chinese Journal of Dermatology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the profile of proliferating T cells and dendritic cells ( DCs ) in the skin infiltrates of patients with mycosis fungoides ( MF) in different stages. Method Paraffin section and immunohistochemisty with monoclonal antibody were used to detect the expression of special antigen per section. Results The numbers of Ki-67+ cells and cutaneous lymphocyte-associated antigen ( CLA+) cells both increased significantly in the skin infiltrates of MF. Most Ki-67+ cells expressed both CLA and CD4 antigen. The number of Ki-67+ cells was significantly higher ( P
