Oddi sphincter lesions:a clinical and histological study
	    		
		   		
	    	
    	
    	
   		
        
        	
        		- VernacularTitle:Oddi括约肌病变的临床与组织学研究
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Jianguo ZHAO
			        		
			        		;
		        		
		        		
		        		
			        		Zhuoyong QUAN
			        		
			        		;
		        		
		        		
		        		
			        		Kaiqin PENG
			        		
			        		;
		        		
		        		
		        		
			        		Ling ZHU
			        		
			        		;
		        		
		        		
		        		
			        		Wen LIU
			        		
			        		;
		        		
		        		
		        		
			        		Yongsheng SHAO
			        		
			        		;
		        		
		        		
		        		
			        		Yingtian ZHANG
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Oddi′s sphincter;
			        		
			        		
			        		
				        		Biopsy;
			        		
			        		
			        		
				        		Sphincterotomy,endoscopic
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of General Surgery
	            		
	            		 1994;0(05):-
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To explore the relationship between the histological alterations of Oddi sphincter lesions and clinical manifestations. MethodsFrom October 1995 to May 2003, biopsies of Oddi sphincter were undertaken during  transduodenal sphincteroplasty (TSP) in 32 cases. Specimens were stained with Van Gieson  Mason staining.  ResultsThirty  one out of 32 specimens were found with  histological alterations in Oddi sphincter including diffuse fibrosis in 87  1% (27/31) , adenomyosis in 2 cases and chronic inflammatory infiltration in 2 cases.  Impacted stone in the terminal common bile duct, benign papillary stenosis and visible postpancreatitis parenchymal changes were all found accompanying severe fibrosis of Oddi sphincter. ConclusionIn patients with impacted stones in the ampulla,  intracholedochal sludge with recurrent cholangitis, and relapsing pancreatitis, endoscopic sphincterotomy is recommended.