Alteration of serum free fatty acids during the carbon tetrachloride-induced fatty liver in rats
- VernacularTitle:四氯化碳性脂肪肝血清游离脂肪酸谱变化
- Author:
Ming YAN
;
Fanli MENG
;
Ruijuan L
;
Xiaoqing JIA
;
Xiancun ZHAO
- Publication Type:Journal Article
- Keywords:
Carbon tetrachloride;
Fatty liver;
Fatty acids, nonesterified;
Chromatography
- From:
Chinese Journal of Pathophysiology
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the alteration of serum free fatty acids in the carbon tetrachloride-induced fatty liver. METHODS: Drug-induced fatty liver rat models were built by injection 40% CCl_4. Serum free fatty acids were analyzed by gas chromatography. RESULTS: In the composition of serun free fatty acids, polyunsaturated fatty acids [oleic acid C18∶1,(28.672?7.332 ?/mg?L~(-1) vs 41.373?2.180 ?/mg?L~(-1)), linoleic acid C18∶2(16.739?0.871 ?/mg?L~(-1) vs 24.959?5.325 ?/mg?L~(-1)), arachidonic acid C20∶4(6.105?2.656 ?/mg?L~(-1) vs 9.802?0.779 ?/mg?L~(-1)),P
