Preparation and Quality Control of Dianozol Effervescent Suppository
- VernacularTitle:达那唑泡腾栓的制备及质量控制
- Author:
Junyong JIANG
;
Yanan ZHOU
;
Chuanbing GU
;
Xigui PANG
- Publication Type:Journal Article
- Keywords:
Dianozol;
effervescent suppository;
preparation;
quality control
- From:
China Pharmacy
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To prepare the Dianozol effervescent suppository and establish the standard of quality con?trol.METHODS:Semi-synthetic glyceride was used as the base material,Dianozol as main ingredient,sodium bicarbonate and citric acid as foaming agents.The UV-spectrophotometry was used for quantitative analysis.RESULTS:The calibration curve of Dianozol was linear in the range of7～24?g/ml(r=0.9999).The recovery rate of Dianozol was100.26%,RSD=0.18%(n= 5).CONCLUSION:The Dianozol effervescent suppository was feasible in technological process.The method of content deter?mination is simple and accurate.
