Clinical study on the treatment of severe acute pancreatitis with combination of sandostatin and growth hormone
- VernacularTitle:善宁和生长激素联合应用治疗重症急性胰腺炎的临床研究
- Author:
Hongping BAO
;
Denghua FANG
;
Ruigang GAO
;
Haolei YANG
;
Kui LI
;
Xuesong ZHANG
;
Tianxu LIU
- Publication Type:Journal Article
- Keywords:
PANCREATITIS/drug ther;
ACUTE DISEASES;
SANDOSTATIN/ther use;
GROWTH HORMONE/ther use;
DRUG THERAPY,COMBINATION
- From:
Chinese Journal of General Surgery
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the therapeutic effect of combination of sandostatin and growth hormone (GH) in the treatment of severe acute pancreatitis (SAP ). Methods Sixty patients with SAP were divided randomly into 3 groups:(1)Sandostatin treatment(ST) group (n=15);(2)combination of sandostatin with GH treatment(CT) group (n=30) ;(3)control group (n=15). The changes in serum IL-1, IL-6,TNF-? and albumin levels after treatment, and the incidence of complications, the duration of hospital stay and cost were compared among the 3 groups. Results The complications, mortality, duration of hospital stay in the CT group were significantly shorter than those in ST group and control group (all P
