Significance of N-ras Oncogene Expression in Acult Myelogenous Leukemia
- VernacularTitle:急性髓细胞性白血病N-ras癌基因表达的意义
- Author:
Zhengfa LI
;
Xiaomei SHENG
;
Keqian SHI
- Publication Type:Journal Article
- Keywords:
Leukemia,Myelogenous,Acult;
Oncogene,N-ras;
Reverse transcriptase-polymerase chain reaction
- From:
Journal of Chinese Physician
2002;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the effect of N-ras oncogene expression in acute myelogenous leukemia(AML).Methods N-ras oncongene in 10 cases of AML were determined using reverse transcriptase-polymerase chain reaction(RT-PCR).Results 3/10 cases were the positive expression,the positive rates were 30%;2/3 patients were treated to complete remmision(CR).Their N-ras oncogene change negative,1/3 patients was no remmision(NR),his N-ras oncogene change negative,1/3 patient was no remmision(NR),his N-ras oncogene keeps positive and dead after 4 months.Conclusions Determination of the N-ras oncogene expression in AML has worthy for diagnose and prognosis.
