Expression of TNF alpha Receptor p75in Skin and Sera of Patients with Psoriasis Vulgaris
- VernacularTitle:寻常性银屑病患者皮肤和血清中肿瘤坏死因子?受体p75测定
- Author:
Kuibin GAO
;
Jiuhong LI
;
Yakun WANG
;
Zaifu LIANG
;
Fangji SONG
;
Hongduo CHEN
- Publication Type:Journal Article
- Keywords:
Psoriasis;
Receptors,tumor necrosis factor
- From:
Chinese Journal of Dermatology
1995;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the role of tumor necrosis factor(TNF)?receptor75000(p75)in psoriasis vulgaris.Methods Expression of p75was detected by immunohistochemistry and enzyme-linked immunosorbent assay(ELISA)in skin and sera of patients with psoriasis vulgaris.Results Expression of p75was not found in skin of normal controls.p75expression was noted in epidermis of lesional and non-le-sional psoriatic skin,and in dermal infiltrating mononuclear cells(MNCs)of psoriatic skin.The staining in-tensity of p75on epidermal keratinocytes(EKCs)was significantly correlated(r' s =0.732,P
