Effect of brief mesenteric artery occlusion on cardiac myocyte apoptosis and Bcl-2 during myocardial ischemia/reperfusion in rats
- VernacularTitle:大鼠肠系膜动脉血流短暂阻断对缺血/再灌注心肌细胞凋亡及Bcl-2表达的影响
- Author:
Xingde LIU
;
Yunzhe CHEN
- Publication Type:Journal Article
- Keywords:
Myocardial reperfusion;
Apoptosis;
Gene expression;
Intestine, small;
Rats
- From:
Chinese Journal of Pathophysiology
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To explore the effect of brief mesenteric artery occlusion (MAO) on cardiac myocyte apoptosis and bcl-2 expression during myocardial ischemia/reperfusion (I/R) in rats. METHODS: TUNEL,immunohistochemical and in situ hybridization(ISH) methods were applied in the present study. RESULTS: ① The numbers of positive cardiac myocyte nuclear and the percentage of positive cardiac myocyte nuclear in MAO+IR 3h group decreased significantly ( P
