Study on Genetic Epidemiology of Systemic Lupus Erythematosus
- VernacularTitle:系统性红斑狼疮遗传流行病学研究
- Author:
Dongqing YE
;
Xiaoming SHI
;
Wei LU
;
Xiangpei LI
;
Yisong HU
;
Shigui YANG
;
Yuanyong XU
- Publication Type:Journal Article
- Keywords:
Systemic lupus erythematosus;
Heritability;
Prevalence rate;
Proband
- From:
Chinese Journal of Dermatology
1995;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
control relatives.A ratio of s/q approached1/q with Penrose' s method.Heritability of SLE was78.8%?4.45%in the first-degree relatives,58.8%?10.9%in the second-degree relatives,and39.2%?32.0%in the third-degree relatives.The weighted mean heritability was75.2%?4.12%.Conclusions SLE has characteristics of polygenic disease.Genetic factor might play an important role in the liability of SLE.
