Changes of PGE_2, PGI_2 and TXA_2 concentration in rat traumatic pulpitis
- VernacularTitle:牙髓创伤时牙髓PGE_2、PGI_2和TXA_2浓度改变的研究
- Author:
Jianbo PAN
;
Shiguang HUANG
;
Huadong WANG
;
Chaofeng HU
;
Lian YAN
- Publication Type:Journal Article
- Keywords:
Pulpitis;
Thromboxane A 2;
Prostaglandins E;
Prostaglandins I
- From:
Chinese Journal of Pathophysiology
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the relationship between prostaglandins and acute pulpitis. METHODS: Rat traumatic pulpitis model was established by pulp exposure. The kinetic pathological changes in dental pulpal tissues and changes of PGE 2?6-Keto-PGF 1? and TXB 2 concentration in dental pulp were observed. RESULTS: After pulpal trauma, the dental pulp showed inflammatory changes and the concentrations of PGE 2?6-Keto-PGF 1? and TXB 2 were increased, which peaked at 6 hour post-trauma. CONCLUSION: Prostaglandins play a significant role in the pathogenesis of pulpitis.
