The Effoct of Superior Cervical Ganglion Resection on the Endolymphatic Sac Blood Flow
- VernacularTitle:颈上神经节切除对豚鼠内淋巴囊血流量影响机制的研究
- Author:
Yanling DOU
;
Huaizhi FENG
;
Zhaohua LIU
- Publication Type:Journal Article
- Keywords:
Endolymphatic sac Superior cervical ganglion Substance P Calcitonin gene-related peptide Endolymphatic sac blood flow Guinea pig
- From:
Journal of Audiology and Speech Pathology
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of substance P (SP), calcitonin gene-related peptide (CGRP) on the blood flow and the function of endolymphatic sac (ES) in guinea pigs to clarify the pathogenesis of some inner ear diseases further.Methods The guinea pig model of superior cervical ganglion (SCG) resection was set up. The ESs of the model animals were stained by SP and CGRP immunocytochemically. The staining images were analysed by the computer. The ESBF was measured with the biologic microphere method.Results Compared with the control group, the staining of SP decreased sharply in the model group, however, the staining of CGRP remained unchanged. In the model animals, the ESBF was decreased either.Conclusion SP and CGRP could take part in the regulation of ESBF to affect the function of ES further.
