Treatment of primary liver cancer by liver cancer vaccine activated TIL
- VernacularTitle:肝癌疫苗激活的肿瘤浸润性淋巴细胞治疗原发性肝癌的研究
- Author:
Ting LI
;
Jianyong LIU
;
Jianlun LIU
- Publication Type:Journal Article
- Keywords:
Cancer vaccines;
Carcinoma, hepatocellular;
Lymphocytes, tumor-infiltrating
- From:
Chinese Journal of General Surgery
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the effects of liver cancer vaccine activated TIL on primary liver cancer (PLC).Methods Twenty-six patients with PLC were treated with stimulated TIL by liver cancer vaccine. The CD3?CD4?CD8?CD4/CD8, NK activity and levels of serum sIL-2R were assayed before and after the treatment, the survival tates of 1, 2 and 3 year were analysed. ResultsCD3?CD4?CD4/CD8 and the activity of NKC were 55?3?76?5;28.3?1.6?44.6?2.3;1.19?0.22?2.21?0.36;9.8?1.2?17.4?2.2, at 19th and 30th day, respectively after treatment of TIL. The difference was all significant compared with the controls (P
