Determination of the Contents of Three Ingredients in Comedo Gel
- VernacularTitle:面刺凝胶中3种成分的含量测定
- Author:
Dong LUO
;
Xiong XIONG
;
Limin CHEN
;
Xiaolan CHEN
- Publication Type:Journal Article
- Keywords:
gel;
multiwavelengh coefficient spectrophotometry;
content determination
- From:
China Pharmacy
1991;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a method for determining the contents of spironolactone chloramphenicol and metromidazole in Mianchi gel.METHODS:The concentrations of three main ingredients were determined by multiwavelengh coefficient spectrophotometry,the detecting wavelenghs being 239.0nm,276.0nm and 313.5nm respectively.RESULTS:The average recoveries and RSDs(n=5)were:spironolactone 99.5%,RSD=3.02%,chloramphenicol 101.61%,RSD=1.47%,metromidazole 101.47%,RSD=2.00%.CONCLUSION:This method is simple,rapid and accurate.It is good for determination of multicomponent preparation.
