Relation between telomerase activity and chronic myelocytic leukemia course
- VernacularTitle:端粒酶活性与慢性粒细胞白血病病程关系的研究
- Author:
Xiaohua NI
;
Fuyong BI
;
Gentao CAO
- Publication Type:Journal Article
- Keywords:
Telomere;
Bone marrow;
Leukmia, myeloid, chronic
- From:
Chinese Journal of Pathophysiology
1989;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: Studying the relation between telomerase activity and chronic myelocytic leukeed(CML) courses by detect telomerase activity(TMA) Of mononuclear cells of bone marrow samples in different CML phases. METHOD: Using telomerase PCR - ELISA method. RESULTS: Telomelase activity of nounal bone marrow is 9. 85 ?0.68, CML chronic phase is 24.48 ?12. 73 which is significantly higher than that of normal bone marrow(P 0.05), at remisson TMA is 18. 12? 6.27 which is shil higher than normal group (P
