The changes of oxygen free radicals in isoproterenol-induced myocardial infarction and its significance
- VernacularTitle:异丙肾上腺素性心肌缺血大鼠全身重要脏器自由基系统的改变及其意义
- Author:
Chuanren DONG
;
Jinbao LIU
- Publication Type:Journal Article
- Keywords:
Isoproterenol;
Myocardial infarction;
Free Radicals
- From:
Chinese Journal of Pathophysiology
1989;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The MDA contents, SOD and. GSH-Px activities of the heart, liver, brain, kidney and serum were observed systematically in isoprotercnol-induced myocardial infarction. The results suggested that the MDA contents, SOD and GSH-Px activities were increased in ischemic myocardium. Oxygen free radicals exerted detrimental effects on vitals organs, and also was accompanied by a compensatory increase of SOD and GSH-Px activities.
