Optimization of Extraction Technology for Tibetan Medicine Duoxuekang by Uniform Design
10.6039/j.issn.1001-0408.2017.10.17
- VernacularTitle:均匀设计法优化藏药多血康提取工艺
- Author:
Xiumei LYU
;
Jing WANG
;
Kehui ZHAO
;
Jing ZHANG
;
Xianrong LAI
;
Gang FAN
;
Yi ZHANG
;
Zangjia GENG
- Keywords:
Tibetan medicine;
Duoxuekang;
Uniform design;
Salidroside;
Gallic acid;
Content;
Extraction;
Technology opti-mization
- From:
China Pharmacy
2017;28(10):1361-1364
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To optimize the extraction technology of Duoxuekang. METHODS:Using comprehensive score of salidroside,gallic acid content and extraction yield as indexes,U6(63)uniform design was designed to optimize the liquid-solid ra-tio,ethanol volume fraction and extraction time of Duoxuekang,then optimize extraction times,and verification test was conduct-ed. RESULTS:The optimal extraction technology was as follows as 50% ethanol,liquid-solid ratio of 1:14,soaking time of 1.5 h,reflux extraction for 1 h and repeated twice;the average extraction yield in 3 tests was 50.18%,contents of salidroside and gal-lic acid were 1.82 mg/g,16.54 mg/g (RSD≤0.84%,n=3). CONCLUSIONS:The optimized extraction technology for Duox-uekang is reasonable,simple and feasible.
