Effect of Selective beta-1 Adrenoreceptor Blocker on Exercise Tolerance in Patients with Hypertention
10.3969/j.issn.1006-9771.2017.04.018
- VernacularTitle:选择性β1受体阻滞剂对高血压患者运动耐力的影响
- Author:
Shoulin LI
;
Yan ZHANG
;
Jie LIU
;
Wei YANG
;
Lijun LIU
;
Zhichang ZHENG
;
Wei LIN
;
Xiaorong WANG
;
Guodong WANG
;
Lihong FENG
;
Siyuan CHEN
;
Zufu YANG
- Keywords:
hypertension;
selective beta-1 adrenoreceptor blocker;
cardiopulmonary exercise testing
- From:
Chinese Journal of Rehabilitation Theory and Practice
2017;23(4):446-448
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of selective beta-1 adrenoreceptor blocker on exercise tolerance in patients with hyperten-sion. Methods From May, 2015 to May, 2016, 72 patients with hypertension were divided into two groups, according to whether taking the selective beta-1 receptor blocker. Group A (n=35) took the selective beta-1 receptor blocker two weeks before cardiopulmonary exercise, while group B (n=37) did not take anything at the same time. The exercise tolerance was compared between two groups. Results The maxi-mal systolic blood pressure, peak heart rate, one-minute heart rate after exercise (HR1) and rate-pressure product were lower in group A than in group B (t>2.012, P<0.05), however, the recovery value of HR1 was higher in group A than in group B (t=2.100, P<0.05). There was no difference in both peak power and peak oxygen uptake between two groups (t<0.689, P>0.05). Conclusion The selective beta-1 adrenore-ceptor blocker could reduce myocardial oxygen consumption, and improve vagus nerve activity, but did not reduce exercise tolerance in pa-tients with hypertension.
