Advances of febrile infection-related epilepsy syndrome
10.3760/cma.j.issn.2095-428X.2016.24.021
- VernacularTitle:热性感染相关性癫痫综合征研究进展
- Author:
Jingshi CHEN
;
Yan DONG
;
Runchun ZHANG
;
Lili WANG
;
Aifang GUO
- Keywords:
Status epilepticus;
Refractory epilepsy;
Fever;
Child
- From:
Chinese Journal of Applied Clinical Pediatrics
2016;31(24):1917-1920
- CountryChina
- Language:Chinese
-
Abstract:
Febrile infection -related epilepsy syndrome(FIRES)is a newly named entity of epileptic encepha-lopathy in recent years.As one of the hot spots studied by domestic and foreign scholars,the etiology and pathogenesis of FIRES,which has a poor treatment and outcome,are undefined.It manifests with refractory seizures and status epilep-ticus in previously healthy school -aged children after banal febrile illness.In addition,with the negative response to currently available treatments,there are a poor prognosis and a high mortality rate in FIRES.Survivors are typically left with refractory partial epilepsy and severe cognitive impairment.Through domestic and foreign literature,this article re-views the potential pathogenesis,clinical features,treatment and prognosis of the syndrome,and provides theoretical ba-sis and new ideas for clinical diagnosis and treatment.
