Research progress of Tanshinones
10.3969/j.issn.1001-1978.2016.12.004
- VernacularTitle:丹参酮类化合物研究进展
- Author:
Huiying LIU
;
Changtao JIANG
;
Juan FENG
;
Xian WANG
- Keywords:
Tanshinones;
clinical appacation;
pharmacologic effects;
therapeutic mechanism;
pharmacokinetics;
pharmaceutic evaluation
- From:
Chinese Pharmacological Bulletin
2016;32(12):1643-1647
- CountryChina
- Language:Chinese
-
Abstract:
Salvia miltiorrhiza bunge (Dan shen in Chinese)is extracted from dried roots and rhizomes of Labiatae Salvia.Tan-shinones are the main lipid-soluble components in Salvia,each has specific pharmacological activity.This review focuses on the research progress of Tanshinones on cardiovascular diseases,an-ti-inflammatory and immunomodulatory effects, anti-tumor effect,hepatocyte protection and neuroprotective effects.Thera-peutic effects and mechanisms of Tanshinones on diverse disea-ses are summarized,pharmacokinetics and pharmaceutic evalua-tion were concluded.This review provides a global understand-ing about Tanshinones as a class of effective and promising can-didates for further studies,and lays a foundation for developing new Tanshinone-based agents according to the characteristics of Tanshinones.
