Collaborative Cross mice and precision medicine
10.3969/j.issn.1671-7856.2016.08.004
- VernacularTitle:复杂性状遗传 CC 小鼠与精准医学研究
- Author:
Peng DU
;
Mengyi CHEN
;
Chengcheng LI
;
Feiyue FAN
;
Aimin MENG
- Publication Type:Journal Article
- Keywords:
Precision medicine;
The Collaborative Cross;
Quantitative trait locus(QTL)
- From:
Chinese Journal of Comparative Medicine
2016;26(8):30-35
- CountryChina
- Language:Chinese
-
Abstract:
The individual variability should be considered in precision medicine-prevention and treatment strategies.Medical research using genomics, proteomics, metabolomics, systems analyses, and other modern tools has made big progress.In 2002, the members of the Complex-Trait Consortium proposed to develop a new mouse genetics resource called the Collaborative Cross (CC).The CC is a genetic reference panel of recombinant inbred lines of mice, designed for the dissection of complex traits and gene networks.It will provide a powerful measure for functional studies of biological networks, which will be essential to understand the intricacies of disease processes.
