Animal models in diabetes mellitus research
10.3969/j.issn.1671-7856.2016.09.015
- VernacularTitle:糖尿病研究中的动物模型进展
- Author:
Dan SONG
;
Liyuan RAN
;
Rujiao JIANG
;
Yingjie WU
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Animal models;
Genetic engineering
- From:
Chinese Journal of Comparative Medicine
2016;26(9):83-87
- CountryChina
- Language:Chinese
-
Abstract:
In spite of much progress on its mechanism, diagnosis and treatment, diabetes mellitus remains a public health challenge. The harm of diabetes is not significantly reduced, instead shows an increasing tendency year by year. To achieve an in?depth and comprehensive understanding of the underlying mechanism, and to develop efficacious, stable and hypoglycemia?risk free drugs, it is crucial to gain more knowledge about diabetes from animal models. In this review, the types of diabetes animal models, modeling methods, the advantages and disadvantages, their applicable scope are discussed aiming to provide a reference for researchers to choose appropriate animal models.
