Diagnostic value of HbA1 c combined with u -ALB in early type 2 diabetes
10.3760/cma.j.issn.1008-6706.2016.20.031
- VernacularTitle:糖化血红蛋白与尿微量白蛋白联合检测诊断早期2型糖尿病肾病的价值
- Author:
Huarong ZHENG
;
Jianjun HU
;
Yan YAO
;
Ying LU
- Publication Type:Journal Article
- Keywords:
Diabetic nephropathy;
Type 2 diabetes;
HbA1c;
u -ALB
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(20):3159-3162
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of glycated hemoglobin(HbA1c)and urine trace albumin (u -ALB)content in early diagnosis of type 2 diabetic nephropathy.Methods 200 patients with type 2 diabetes were selected as diabetes group,and 30 cases of healthy people as control group.According to the content of HbA1c, the diabetes patients were re -divided into low group (HbA1c <7%),the median group(7.1%≤HbA1c≤10%) and high value group (HbA1c >10.1%).The levels of HbA1c and u -ALB were detected and the correlation between them was calculated.Results The values of HbA1c (8.85 ±1.22)% and u -ALB (88.3 ±12.4)mg/L in the diabetes group were significantly higher than those of the control group (t =10.88,54.25,all P <0.05);The level of HbA1c in the high,medium and low group[(11.02 ±1.37)%,(8.45 ±2.01)%,(6.88 ±1.23)%]were consistent with the levels of the respective levels of fasting glucose[(13.22 ±2.05)mmol/L,(9.25 ±1.28)mmol/L, (6.27 ±0.63)mmol/L].HbA1c and constituting the u -ALB levels were positively correlated in the high,medium and low group(r =0.452,0.512,0.452,all P <0.05).Conclusion The combined detection of HbA1c and u -ALB levels has important value for early diagnosis of type 2 diabetic nephropathy.
