Optimization of the Extraction Technology of Compound Epimedium Chewable Tablets by Orthogonal Test
10.6039/j.issn.1001-0408.2015.28.32
- VernacularTitle:正交试验法优选复方淫羊藿咀嚼片的提取工艺
- Author:
Chan MOU
;
Ruopeng ZHOU
;
Yingying LAI
- Publication Type:Journal Article
- Keywords:
Compound epimedium chewable tablets;
Icariin;
Crude polysaccharides;
Orthogonal test;
Extraction technology
- From:
China Pharmacy
2015;(28):3986-3988
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To optimize the extraction technology of Compound epimedium chewable tablets. METHODS:Using the extraction rate of icariin,the content of crude polysaccharide and yield of extractum as index,the effects of water amount,ex-traction time and extraction times on extraction effect were investigated by orthogonal test. The extraction technology was optimized and validation test was conducted. RESULTS:The optimized extraction technology was as follows as 6-fold water,extracting 3 times,2 h each time. The validation test showed that the average extraction rate of icariin was(83.80±0.02)%,the average con-tent of crude polysaccharide was (29.28 ± 0.55) mg/g,and the average yield of extractum was (28.47 ± 0.29)%(RSD≤0.55%, n=3). CONCLUSIONS:The optimized extraction technology is stable,and can be used for the extraction of Compound epimedi-um chewable tablets.
