Efficacy of Yixinshu Capsule in the Adjuvant Treatment of Angina Pectoris:A Meta-analysis

VernacularTitle:益心舒胶囊辅助治疗冠心病心绞痛有效性的Meta分析
Author: Wen TANG ; Jianling TAN ; Liangliang JIA ; Guilan JIN
Publication Type:Journal Article
Keywords: Yixinshu capsule; Angina pectoris; Effectiveness; Meta-analysis
From: China Pharmacy 2016;27(3):351-353
CountryChina
Language:Chinese
Abstract: OBJECTIVE:Tosystematically evaluate the efficacy of Yixinshu capsule in the adjuvant treatmentof angina pecto-ris,and provide evidence-based reference for clinical treatment. METHODS:Retrieved from CJFD,VIP Database,Wanfang Data-base,Medline and EMBase,randomized controlled trials(RCT)about the efficacyof Yixinshu capsule(test group)versus other drugs (control group) in the adjuvant treatment of angina pectoris were collected. Meta-analysis was performed bu using Rev Man 5.2 software after data extraction and quality evaluation by modified Jadad. RESULTS:Totally 11 RCTs were enrolled,involving 1 827 pa-tients. Results of Meta-analysis showed the total effective rate of angina pectoris improvement [OR=0.30,95%CI(0.23,0.40),P<0.001] and electrocardiogram improvement [OR=0.52,95%CI(0.41,0.66),P<0.001] in test group were significantly higher than control group,there was significant difference between 2 groups. CONCLUSIONS:Yixinshu is effective for the adjuvant treatment of angina pectoris.