Intervention Effect of DRUGS System on Antibacterial Agents Use in Department of Obstetrics and Gyne-cology in Our Hospital
	    		
		   		
		   			
		   		
	    	
    	 
    	10.6039/j.issn.1001-0408.2016.08.41
   		
        
        	
        		- VernacularTitle:合理用药决策系统对我院妇产科抗菌药物使用的干预效果分析
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Fangqin XU
			        		
			        		;
		        		
		        		
		        		
			        		Chao GUO
			        		
			        		;
		        		
		        		
		        		
			        		Yang LU
			        		
			        		;
		        		
		        		
		        		
			        		Yanrong ZHU
			        		
			        		;
		        		
		        		
		        		
			        		Guo WEI
			        		
			        		;
		        		
		        		
		        		
			        		Miaomiao XI
			        		
			        		;
		        		
		        		
		        		
			        		Aidong WEN
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Drug Rational Usage Guidelines System;
			        		
			        		
			        		
				        		Antibacterial agents;
			        		
			        		
			        		
				        		Department of obstetrics and gynecology;
			        		
			        		
			        		
				        		Interven-tions
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			China Pharmacy
	            		
	            		 2016;27(8):1133-1135
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	OBJECTIVE:To analyze intervention effect of Drug Rational Usage Guidelines System(DRUGS)on antibacterial agents use in department of obstetrics and gynecology in our hospital. METHODS:The application of antibacterial agents in depart-ment of obstetrics and gynecology in our hospital during Jan.-May(before intervention)and Jun.-Nov. 2012(after intervention)were extracted in respects of drug name,preoperative medication duration,perioperative additional condition,postoperative drug with-drawal time,drug combination,usage and dosage,average hospitalization stay,hospitalization cost. The intervention effects were analyzed. RESULTS:After intervention,the type of antibacterial agents were more in line with national regulations;the proportion of type Ⅰ incision surgery without antibacterial agents increased from 57.8% to 75.2%;the prophylactic application of antibacteri-al agents in type Ⅱ incision surgery within 0.5-2 h increased from 80.2% to 97.0%. The rate of reasonable antibacterial selection, drug combination,usage and dosage increased from 76.9%,64.9%,71.3% to 89.3%,84.6%,90.2%,respectively. The average hospitalization stay and antibacterial cost per capita decreased significantly. There was statistical significance among above indica-tors before and after intervention(P<0.05 or P<0.01). CONCLUSIONS:DRUGS effectively change irrational use of antibacterial agents in department of obstetrics and gynecology,which provide a new method for the management of antibacterial agents.