In vitro treatments of Echinococcus granulosus with fungal chitosan, as a novel biomolecule
10.1016/S2221-1691(13)60160-4
- Author:
Rahimiesboei BAHMAN
;
Fakhar MAHDI
;
Chabra AROONA
;
Hosseini MAHBOOBEH
- Publication Type:Journal Article
- Keywords:
Chitosan;
Protoccoleces;
Echinococcus granulosus;
Penicillium
- From:Asian Pacific Journal of Tropical Biomedicine
2013;(10):811-815
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To determined the antiparasitic activity of the isolated chitosan from Penicillium viridicatum, Penicillium aurantiogriseum and commercial chitosan against protoscolicidal of hydatid cysts were determined.
Methods:After isolating chitosan from fungal cell walls, four concentrations (50, 100, 200, 400μg/mL) of each type of prepared chitosan and commercial chitosan were used for 10, 30, 60, and 180 min, respectively.
Results: Among different type of chitosan, commercial chitosan with the highest degree of deacetylation showed high scolicidal activity in vitro. Fungal chitosan could be recommended, as good as commercial chitosan, for hydatic cysts control.
Conclusions:It seems to be a good alternative to synthetic and chemical scolicidal.
