Research on distribution of gastrointestinal peptide glucagon-1 of positive cells in tree shrews
10.11659/jjssx.03E015054
- VernacularTitle:树鼩消化道胰高血糖素样肽-1阳性细胞分布的研究
- Author:
Lixiong CHEN
;
Junbin WANG
;
Ruwen LIU
;
Longbao LYU
;
Liling CHEN
- Publication Type:Journal Article
- Keywords:
glucagon-1;
digestive tract;
tree shrew;
model
- From:
Journal of Regional Anatomy and Operative Surgery
2016;25(4):255-257
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe tree shrews gastrointestinal glucagon like peptide 1 ( glp-1 ) immune response positive cells ( EG cells) distribution and the difference of the digestive tract of rats.Methods Immunohisto chemical SABC method to detect tree shrews diges-tive tract (except for oral cavity, pharynx) glp-1 cells positive content.Results EG cells distributed in tree shrews duodenum,ileum and colon,glandular epithelial cells of jejunum,positive material is distributed in the cytoplasm.Tree shrews stomach,rectum did not see EG cell distribution.Ileal immune dyeing results show positive,EG cells of the digestive tract,only the ileum and colon distribution glp-1 more posi-tive, tree shrews compared with the rats in the digestive tract glp-1 significant difference (P<0.01).Conclusion Gastrointestinal tree shrew in duodenum,ileum and colon,jejunum have glucagon positive cells.The rat only have positive cells in the ileum and colon.According to the mechanism of the glp-1 and the distribution of tree shrews gastrointestinal glp-1,tree shrews atherosclerosis ( atherosclerosis,AS) AS the model is not easy to make may be associated with the role of glp-1.
