Safety and Efficacy of Percutaneous Ventricular Partitioning in Ischemic Heart Failure Patients With Apical Aneurysm
10.3969/j.issn.1000-3614.2016.08.012
- VernacularTitle:经皮左心室分隔术对心尖部室壁瘤形成的缺血性心力衰竭患者的安全性及疗效评估
- Author:
Jian WANG
;
Bin WANG
;
Guosheng XIAO
;
Tao YE
;
Mingri ZHENG
;
Maolong SU
;
Feng QIU
;
Keke LAI
;
Qian YANG
;
Hongmei WEN
;
Yan WANG
- Publication Type:Journal Article
- Keywords:
Percutaneous ventricular partitioning;
Parachute;
Heart failure;
Cardiac aneurysm
- From:
Chinese Circulation Journal
2016;31(8):775-779
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the safety and efifcacy of percutaneous ventricular partitioning (PVP) in ischemic heart failure (IHF) patients with apical aneurysm. Methods: A total of 19 IHF patients with apical aneurysm at the age of (68.1 ± 8.2) years were enrolled. The patients received PVP operation with adequate clinical and medical imaging examinations; the safety of operation was evaluated and post-operative clinical events with cardiac function were followed-up. Results: There were 18/19 (95%) patients with successful PVP and 1 had to stop the operation due to unsatisfactory landing of ventricular partitioning device. 2 patients suffered from vessel access related complication and received femoral artery stent implantation. With (252 ± 170) days follow-up study, no post-operative device failure, cardiac death, thromboembolism and HF re-hospitalization occurred. At 3 months after operation, the patients had improved NYHA classiifcation (2.72 ± 0.67) vs (1.67 ± 0.59) and 6 min walk test (462 ± 96) m vs (484 ± 87) m, bothP<0.01. Echocardiography indicated that post-operative left ventricle end-diastolic volume index (LVEDVI) decreased form (137.4 ± 19.1) ml/m2 to (125.6 ± 18.5) ml/m2,P=0.0056 and LVESVI decreased from (89.7 ± 22.3) ml/m2 to (78.8 ± 20.7) ml/m2,P=0.0019; while LVEF increased from (34.8 ± 8.13) % to (41.3 ± 6.2) %, P=0.031. Conclusion: Our preliminary experience showed that with adequate evaluation, PVP was safe and effective in IHF patients with apical aneurysm; short-term follow-up study implied the improved hemodynamic and cardiac function.
