Roles of CD200 and CD200R in cerebral ischemia
10.3760/cma.j.issn.1673-4165.2016.04.013
- VernacularTitle:CD200和CD200R在脑缺血中的作用
- Author:
Heng XU
;
Wenqian WU
;
Shoucai ZHAO
;
Fudong LIU
- Publication Type:Journal Article
- Keywords:
Brain Ischemia;
Antigens,CD;
Microglia;
Inflammation;
Antigens,CD200
- From:
International Journal of Cerebrovascular Diseases
2016;24(4):378-381
- CountryChina
- Language:Chinese
-
Abstract:
Inflammation plays an important role in the pathophysiological mechanism of acute ischemic stroke.CD200 expressed in neurons interacts with CD200 receptor (CD200R) on microglia cells.It can inhibit microglia activation and alleviate the inflammation after cerebral ischemic injury.This article reviews the roles of CD200 and CD200R in the activation of microglia after cerebral ischemia.
