Kisspeptin-A new link bridging energy homeostasis and reproduction
10.3760/cma.j.issn.1000-6699.2016.07.003
- VernacularTitle:Kisspeptin--连接能量与生殖的新纽带
- Author:
Junping WEN
;
Gang CHEN
;
Lixiang LIN
- Publication Type:Journal Article
- Keywords:
Energy homeostasis;
Kisspeptin;
Reproduction
- From:
Chinese Journal of Endocrinology and Metabolism
2016;32(7):536-539
- CountryChina
- Language:Chinese
-
Abstract:
[Summary] Kisspeptin is vital for the neuroendocrine regulation of GnRH secretion. Kisspeptin neurons are now recognized as a central pathway responsible for conveying key homeostatic information to GnRH neurons. A number of metabolic modulators have been proposed as regulators of kisspeptin including leptin, adiponectin, insulin, ghrelin, POMC, and neuropeptide Y. Recent data indicate that kisspeptin may have a direct role in regulating energy balance by its regulation of food intake and glucose homeostasis. Thus, kisspeptin may serve as a new connection between reproductive function and energy metabolism.
