The role of YKL-40 in inflammatory response and its related signaling pathways
10.16571/j.cnki.1008-8199.2016.08.022
- VernacularTitle:YKL-40在炎症性疾病中的作用及其信号通路研究进展
- Author:
Yuan HE
;
Mingfang LIAO
;
Lefeng QU
- Publication Type:Journal Article
- Keywords:
YKL-40;
Inflammatory response;
Function;
Signaling pathway
- From:
Journal of Medical Postgraduates
2016;29(8):883-888
- CountryChina
- Language:Chinese
-
Abstract:
YKL-40, a newly found inflammatory marker, is belonged to the mammals′chitinase family.It showed that YKL-40 can participate in a variety of inflammatory diseases such as airway inflammatory diseases, cardiovascular and neurological inflamma-tory diseases, and arthritis etc.It could be used to diagnose and evaluate these inflammatory diseases.Since its specific receptor has not been identified, the exact biological role of YKL-40 in inflammatory response still remains unclear.This article reviews the function of YKL-40 in inflammatory response and its related signaling pathways.
