A Case Control Study for Risk Factors in Patients of Acute Myocardial Infarction Complicated With Cardiac Rupture
10.3969/j.issn.1000-3614.2016.05.006
- VernacularTitle:急性心肌梗死并发心脏破裂危险因素的病例对照研究
- Author:
Longyu LI
;
Zhi JIA
;
Haiqing LIANG
;
Mu GUO
;
Yunqiang ZHANG
;
Yi SONG
- Publication Type:Journal Article
- Keywords:
Cardiac rupture;
Risk factors;
Case control studies
- From:
Chinese Circulation Journal
2016;31(5):442-445
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To analyze clinical characteristics and risk factors in patients with acute myocardial infarction (AMI) complicated with cardiac rupture (CR) and to explore the prevention and treatment strategy in clinical practice. Methods: A case control study was conducted in 2 groups: CR group, the patients with coronary angiography conifrmed AMI with CR,n=44 and Control group, the patients with simultaneous STEAMI and by 1:3 pair-matched ratio,n=132. Clinical information was compared between 2 groups and the relevant risk factors for predicting CR were studied by Logistic regression analysis. Results: Compared with Control group, CR group had the lower ratio of β-receptor blocker application (22.7% vs 81.4%),P<0.05. Univariate regression analysis indicated that lower body mass index, incipient MI, anterior MI, no-reperfusion therapy, delayed reperfusion therapy, lower blood pressure at admission, post-infarction angina, ventricular aneurysm, higher Gensini score, high blood levels of cretinine and BNP, low ejection fraction were the risk factors for CR occurrence in STEAMI patients, allP<0.05. Multivariate regression analysis presented that incipient MI (P<0.049, OR=7.462), post-infarction angina (P<0.000, OR=8.591), ventricular aneurysm (P<0.005, OR=4.617) and higher Gensini score (P<0.001, OR=2.788) were risk factors for CR occurrence in STEAMI patients. Conclusion: Incipient MI, post-infarction angina, ventricular aneurysm and higher Gensini score are the risk factors for CR occurrence in STEAMI patients.
