Quality Control Methods for Qianliedan Particle
- VernacularTitle:前列丹颗粒的质量控制方法研究
- Author:
Lingjun ZENG
;
Hongtao SONG
;
Huihua CHENG
;
Yingli FENG
- Publication Type:Journal Article
- Keywords:
Qianliedan particle;
Quality control;
Scutellarin
- From:
China Pharmacist
2016;19(3):474-477
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish the quality control methods for Qianliedan particle. Methods:TLC was used to identify Scutel-lariae Barbatae Herba, Astragali Radix, Glycyrrhizae Radix Et, Rhizoma Praeparata Cum Melle, Psoraleae Fructus and Curcumae lon-gae Rhizoma. The content determination item was developed by determining the content of scutellarin in Scutellariae Barbatae Herba by HPLC. Results:The TLC spots were clear and well-separated without any interference from the negative sample. A good linear rela-tionship was established between the peak response and the concentration of scutellarin within the range of 3. 96-79. 20 μg·ml-1(r=0. 999 9). The mean recovery of scutellarin was 99. 34% (RSD=1. 25%, n=9). Conclusion:The established quality control meth-ods are accurate, reliable, stable and specific, which can be well used for the quality control of Qianliedan particle.
