Study on viral etiology of acute respiratory tract infections in children in Wuxi area during 2011-2014
10.3760/cma.j.issn.1000-6680.2016.03.008
- VernacularTitle:2011年至2014年无锡地区儿童急性呼吸道病毒感染病原谱研究
- Author:
Guangyuan MA
;
Xia LING
;
Jing BAO
;
Yong XIAO
;
Yayong JI
;
Jialin WU
- Publication Type:Journal Article
- Keywords:
Acute respiratory tract infections;
Viral etiology;
Respirovirus infections
- From:
Chinese Journal of Infectious Diseases
2016;34(3):170-173
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the epidemiology of respiratory viruses in children from Wuxi area.Methods A total of 2 747 cases of children diagnosed with acute respiratory infection in Wuxi during 2011 —2014 were collected.Reverse transcription-polymerase chain reaction was used to detect nine kinds of respiratory viruses,including influenza virus A (Flu A),influenza virus B (Flu B),parainfluenza virus (PIV)Ⅰ-Ⅳ,adenovirus (ADV),respiratory sycytial virus (RSV),human metaneumovirus (hMPV), human bocavirus (HBov),human coronaviruses (hCov)and human rhinovirus (HRV).The categorical data were compared using chi square test.Results A total of 856 among the 2 747 samples were tested positive for respiratory virus nucleic acid,with the positive rate of 31 .16%.The viral distribution was uneven in different seasons,and the infection peaked in winter and spring.The virus detection rate was highest in age 1 to 2 year group (up to 40.18%),and followed by age 6 to 12 year group (32.63%).Flu A virus was the most frequently detected virus,accounting for 7.54% (207/2 747);followed by PIV, accounting for 6.95 % (191/2 747);and Flu B accounted for 4.22%(116/2 747).There were 84 cases of mixed infection of two or more kinds of respiratory viruses,with positive rate of 3.06% (84/2 747 ). Conclusions Our study suggests that Flu A is the most common pathogen in children with acute respiratory infections in Wuxi area during 2011 —2014;virus detection rate is highest in age 1 to 2 year group;and parainfluenza virus is almost detected throughout the year,while the rest of respiratory viruses are commonly seen in winter and spring.
