Relationship between sub-stage of initial high-grade T1 bladder urothelial carcinoma and prognosis
10.3760/cma.j.issn.1000-6702.2015.10.011
- VernacularTitle:原发 T1 G3膀胱尿路上皮癌病理亚分期与预后的关系
- Author:
Yu HAN
;
Qinchao YU
;
Yanwei CAO
;
Yonghua WANG
;
Dezhi YUE
- Publication Type:Journal Article
- Keywords:
Urinary bladder neoplasms;
T1 G3;
Urothelial carcinoma;
Substaging
- From:
Chinese Journal of Urology
2015;(10):765-767
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the impact of sub-stage on the clinical prognosis of T 1 G3 and evaluate the feasibility of the T1me system in pT1G3 sub-staging.Methods The clinical data,pathological specimen and follow-up data were collected from 56 patients out of 87 patients diagnosed with initial high-grade T1 bladder urothelial carcinoma .The patients were divided into Group A [ T1-microinvasive (T1m),17 cases] and group B [T1-extensive-invasive (T1e),39 cases] according to pathological evaluation after transurethral resection.Clinical parameters were analyzed with Chi-square test,and recurrence-free and progression free survival were obtained by Kaplan-Meier analysis and Log-rank test.Results Age,tumor size,number and intravesical instilled medication showed no significant differences between the 2 groups ( P>0.05 ) .There were significant differences of 5-year recurrence-free rate ( P =0.037 ) and progression-free survival rate ( P =0.045 ) between the 2 groups, and the prognosis of group A was significantly better than that of group B .Conclusion The pathological sub-stage is an important predictor in initial high-grade T1 bladder urothelial carcinoma patients , and the T1me system is objective and feasible.
