Correlation of GA/HbA1c ratio with carotid atherosclerosis in type 2 diabetes

VernacularTitle:GA／HbA1c比值与2型糖尿病患者颈动脉粥样硬化斑块相关性
Author: Xu CAO ; Jichuan WU ; Pengqiu LI ; Xuejue ZHANG ; Yang XIAN ; Mingjin BAO ; Yan YANG ; Jun DENG ; Jun FANG
Publication Type:Journal Article
Keywords: Diabetes,type 2; Carotid intima-media thickness; Glycated albumin; GA/HbA1c ratio
From: The Journal of Practical Medicine 2015;(18):2969-2971
CountryChina
Language:Chinese
Abstract: Objective To investigate the association between the glycated albumin to glycated hemoglobin (GA/A1c) ratio and carotid plaque. Methods Type 2 diabetic (T2DM) patients in endocrine inpatient department of Sichuan Provincial People′s Hospital were chosen whose clinical data were collected. Results Of the recruited 154 T2DM patients , GA/HbA1c ratio was negatively correlated with BMI , blood uric acid and was positively correlated with age, HCY, FBG, PBG, left carotid IMT and right carotid IMT. In terms of carotid plaque, GA, GA/HbA1c ratio and HCY were higher in carotid plaque positive patients than those without carotid plaque. The results of logistic regression analysis showed that GA/HbA1c ratio was significantly associated with the presence of carotid plaque (P=0.008). Conclusions GA/HbA1c ratio was positively correlated with the presence of carotid artery IMT in T2DM This suggests that GA/HbA1c ratio will serve as a useful clinical marker for predicting diabetic cardiovascular complications.