Study on liver function and viral lood of pediatric AIDS patients with HBV/HCV co-infection receiving HAART
10.3969/j.issn.1000-484X.2015.10.019
- VernacularTitle:艾滋病合并 HBV／HCV 感染患儿 HAART 治疗后肝功能及病毒载量变化
- Author:
Heping RAO
;
Meixin FANG
;
Wei WANG
;
Weili LU
;
Shuihong YAO
;
Jianhua YE
- Publication Type:Journal Article
- Keywords:
Pediatric AIDS patients;
HBV/HCV;
HAART;
Liver injury;
HIV viral load
- From:
Chinese Journal of Immunology
2015;(10):1385-1388
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the change of liver function,viral load and CD4+T count in pediatric AIDS patients with HBV/HCV co-infection after HARRT therapy,and explore the effect of HBV/HCV co-infection on HAART.Methods:95 pediatric AIDS patients without HBV/HCV co-infection ( group A) ,9 pediatric AIDS patients with HBV co-infection ( group B) and 23 pediatric AIDS patients with HCV co-infection ( group C) who received HAART for 2 year were enrolled.Liver function,viral load and CD4+T count were detected before and after HAART.Results:After HAART for 2 years,26 patients (20.5%) were found with liver injury of grade 2 (1000.05 ) .Conclusion: Co-infection of HBV/HCV can aggravate the liver damage of HIV-1 infected children,but has no significant effect on HAART.
