Effects of alprazolam on capture stress-related serum cortisol responses in Korean raccoon dogs (Nyctereutes procyonoides koreensis).
10.4142/jvs.2011.12.1.103
- Author:
Sun A KIM
1
;
So Yeong LEE
;
Junpei KIMURA
;
Nam Shik SHIN
Author Information
1. College of Veterinary Medicine, Seoul National University, Seoul 151-742, Korea. nsshin@snu.ac.kr
- Publication Type:Case Report ; Research Support, Non-U.S. Gov't
- Keywords:
alprazolam;
capture stress;
cortisol;
Korean raccoon dog;
Nyctereutes procyonoide koreensis
- MeSH:
Alprazolam/*therapeutic use;
Animals;
Anti-Anxiety Agents/*therapeutic use;
Anxiety/*drug therapy;
Hydrocorti;
*Raccoon Dogs;
Republic of Korea;
Restraint, Physical/*veterinary
- From:Journal of Veterinary Science
2011;12(1):103-105
- CountryRepublic of Korea
- Language:English
-
Abstract:
The purpose of this study was to evaluate the effect of alprazolam on the stress that Korean raccoon dogs (Nyctereutes procyonoides koreensis) may experience while caught in a live trap by measuring their serum cortisol response. The animals were placed in a live trap with or without being pretreated with oral doses of alprazolam. In both groups, pre-trap blood samples were initially collected without anesthesia before the animals were positioned in the live trap; then post-trap blood samples were collected after the animals had remained in the live trap for 2 h. Changes in cortisol levels were observed using a chemiluminescent immunoassay. The level of cortisol increased in the control group and decreased in the alprazolam-pretreatment group (p < 0.05). In this study, we demonstrated that alprazolam pretreatment reduced stress during live trap capture.
